Response: TECHNICAL COMMENTS

Technical Comments

S. Gider et al. (1) studied classical and quantum magnetic phenomena in natural and artificial ferritin proteins. If the magnetic moment of the ferritin molecules is blocked below 5 K, as Gider et al. show in figures 1 and 2 of their report (1), then the observed resonance at 24.3 mK, shown in figure 3 of their report, cannot be attributed to quantum oscillations of the magnetic moment between ...

Technical Comments

Shin Takasawa et al. (1) challenge the role of inositol 1,4,5-triphosphate (IP3) as an intracellular second messenger that mobilizes Ca21 in pancreatic P cells. They found that cyclic adenosine diphosphate-ribose (cADP-ribose), but not IP3, releases Ca2+ from islet microsomes. It is difficult to reconcile their results with many studies that establish IP3 as an intracellular Ca2+mobilizing seco...

TECHNICAL COMMENTS Measuring Synaptic Interactions

A. P. Georgopoulos e t al. present novel evidence which suggests that synaptic interactions between pairs of cortical neurons are directly related to the degree to which they fire together during directed limb movements (1).The cover for the issue of 2 April depicts synaptic interactions ranging from strongly excitatory (for cells with similar direction preference) to strongly inhibitory (for c...

TECHNICAL COMMENTS: "Replay" of Hippocampal "Memories".

William E. Skaggs and Bruce L. McNaughton state, in the title of their report, that they found a "Replay of neuronal firing sequences in rat hippocampus during sleep following spatial experience" (1). On the basis of the evidence they present, we question that finding. Skaggs and McNaughton analyzed recordings from pairs of rat hippocampal neurons during a period of running on a closed track an...

Response to Reviewers ’ Comments